Thrombocytopenia After Ibuprofen: A Case Report
Published: February 1, 2009 | DOI: https://doi.org/10.7860/JCDR/2009/.451
JAUHARI AC*,BISTA D**,JOHOREY AC***,SAHA S****,SAHA A*****
*Professor,Dept of Pharmacology,
Mainpal College of Medical Sciences,
Pokhara, (Nepal),**Lecturer, Dept of Clinical Pharmacology,Nepal Medical College,Kathmandu,(Nepal),***Orthopedic Surgeon,Lilawati & Breach Candy Hospitals, Mumbai, (India),****Senior Research Fellow, Department of Pediatrics, All India Institute of Medical Sciences,New Delhi,(India),*****Prof.& HOD, Dept of Pharmacology, Manipal College of Medical Sciences,Pokhara,(Nepal)
Correspondence
Dr. A. C. Jauhari,Prof.,Dept. ofPharmacology,Manipal College of Medical Sciences Pokhara,(Nepal)E-mail: dracjauhari_7@yahoo.co.in
Ibuprofen, a propionic acid derivative, is an important non steroidal anti-inflammatory drug (NSAIDs) used freely for the treatment of various arthritic diseases, and as analgesic and antipyretic drug available over the counter (OTC) in Nepal.
Thrombocytopenia (TPA) is one of the rare haematopoitic adverse drug reactions (ADRs, <1%) of ibuprofen. This is a fatal case of ibuprofen induced TPA, reported from the Nepalese population. Ibuprofen is documented to be one of the safest anti-inflammatory, analgesic and antipyretic drugs used frequently.
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